Fitness costs associated with a GABA receptor mutation conferring dieldrin resistance in Aedes albopictus.

ABSTRACT: Understanding the dynamics of insecticide resistance genes in mosquito populations is pivotal for a sustainable use of insecticides. Dieldrin resistance in Aedes albopictus is conferred by the alanine to serine substitution (A302S or Rdl^R allele) in the γ-aminobutyric acid (GABA) receptor encoded by the Rdl gene. On Reunion Island, dieldrin resistance was initially reported in natural Ae. albopictus populations sampled in 2008 despite the ban of dieldrin since 1994. To monitor insecticide resistance in Ae. albopictus on the island and to identify its drivers, we measured (i) the frequency of resistance alleles in 19 distinct natural populations collected between 2016 and 2017, (ii) fitness costs associated with dieldrin resistance in laboratory-controlled experiments, and (iii)

SUBMITTER: Gomard Y 

PROVIDER: S-EPMC9614001 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature