Plasma human growth cytokines in children with vasovagal syncope.

ABSTRACT:

Purpose

The study was designed to investigate the profile of plasma human growth cytokines in pediatric vasovagal syncope (VVS).

Materials and methods

In the discovery set of the study, plasma human growth cytokines were measured using a Quantiboby Human Growth Factor Array in 24 VVS children and 12 healthy controls. Scatter and principal component analysis (PCA) diagrams were used to describe the samples, an unsupervised hierarchical clustering analysis was used to categorize the samples. Subsequently, the cytokines obtained from the screening assays were verified with a suspension cytokine array in the validation set of the study including 53 VVS children and 24 controls. Finally, the factors associated with pediatric VVS and the predictive value for the diagnosis of VVS w

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9614254 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature