Risk Factors for Failure of Tube Shunt Surgery: A Pooled Data Analysis.

ABSTRACT:

Purpose

To identify the risk factors associated with failure of tube shunt surgery.

Design

Pooled analysis of 3 prospective multicenter, randomized clinical trials.

Methods

A total of 621 patients with medically uncontrolled glaucoma were enrolled, including 276 from the Ahmed Baerveldt Comparison Study, 238 from the Ahmed Versus Baerveldt Study, and 107 from the tube group of the Tube Versus Trabeculectomy Study. Patients were randomized to treatment with an Ahmed glaucoma valve (model FP7) or Baerveldt glaucoma implant (model 101-350). The associations between baseline risk factors and tube shunt failure were assessed using a Cox proportional hazards regression model. The primary outcome measure was the rate of surgical failure defined as intraocular pressure (IOP)

SUBMITTER: Bowden EC 

PROVIDER: S-EPMC9614408 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature