Association of Intraocular Pressure With Retinal Nerve Fiber Layer Thinning in Patients With Glaucoma.

ABSTRACT:

Importance

Higher intraocular pressure variability may be associated with faster structural changes in patients with glaucoma.

Objectives

To investigate the association of mean intraocular pressure and intraocular pressure variability (defined as the SD of intraocular pressure and the intraocular pressure range) with the rate of retinal nerve fiber layer thinning over time in patients with glaucoma.

Design, setting, and participants

In this retrospective analysis of a longitudinal cohort, patients were enrolled from the Diagnostic Innovations in Glaucoma Study and the African Descent and Glaucoma Evaluation study. A total of 815 eyes (564 with perimetric glaucoma and 251 with preperimetric glaucoma) from 508 patients with imaging follow-up for a mean of 6.3 years from

SUBMITTER: Nishida T 

PROVIDER: S-EPMC9614677 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature