Risk of preeclampsia by gestational weight gain in women with varied prepregnancy BMI: A retrospective cohort study.

ABSTRACT:

Introduction

Despite the important clinical significance, limited data on the joint contribution of prepregnancy body mass index (BMI) and gestational weight gain (GWG) to preeclampsia, the second leading cause of maternal mortality worldwide. This study aimed to estimate the risk of preeclampsia by GWG among women with varied prepregnancy BMI.

Methods

We conducted a retrospective cohort study using data of 117 738 singleton pregnant women aged 18-49 years from 150 maternity hospitals in China between 2015 and 2018. GWG was calculated as the measured weight at the time of preeclampsia assessment minus prepregnancy weight; GWG velocity was calculated as the GWG divided by the gestational age at weighing. The non-linear associations of GWG with preeclampsia were examined by re

SUBMITTER: Gong X 

PROVIDER: S-EPMC9616116 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature