Controllability of Structural Brain Networks and the Waxing and Waning of Negative Affect in Daily Life.

ABSTRACT:

Background

The waxing and waning of negative affect in daily life is normative, reflecting an adaptive capacity to respond flexibly to changing circumstances. However, understanding of the brain structure correlates of affective variability in naturalistic settings has been limited. Using network control theory, we examine facets of brain structure that may enable negative affect variability in daily life.

Methods

We used diffusion-weighted imaging data from 95 young adults (age [in years]: mean = 20.19, SD = 1.80; 56 women) to construct structural connectivity networks that map white matter fiber connections between 200 cortical and 14 subcortical regions. We applied network control theory to these structural networks to estimate the degree to which each brain region's patt

SUBMITTER: McGowan AL 

PROVIDER: S-EPMC9616346 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature