cfr and fexA genes in methicillin-resistant Staphylococcus aureus from humans and livestock in the Netherlands.

ABSTRACT:

Background

Although the Netherlands is a country with a low endemic level of methicillin-resistant Staphylococcus aureus (MRSA), a national MRSA surveillance has been in place since 1989. In 2003 livestock emerged as a major reservoir of MRSA and currently livestock-associated MRSA (clonal complex CC398) make up 25% of all surveillance isolates. To assess possible transfer of resistant strains or resistance genes, MRSA obtained from humans and animals were characterized in detail.

Methods

The sequenced genomes of 6327 MRSA surveillance isolates from humans and from 332 CC398 isolates from livestock-related samples were analyzed and resistance genes were identified. Several isolates were subjected to long-read sequencing to reconstruct chromosomes and plasmids.

Resu

SUBMITTER: Schouls LM 

PROVIDER: S-EPMC9616846 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature