Real-time monitoring of the dynamics and interactions of bacteria and the early-stage formation of biofilms.

ABSTRACT: Bacterial biofilms are complex colonies of bacteria adhered to a static surface and/or one to another. Bacterial biofilms exhibit high resistance to antimicrobial agents and can cause life-threatening nosocomial infections. Despite the effort of the scientific community investigating the formation and growth of bacterial biofilms, the preliminary interaction of bacteria with a surface and the subsequent early-stage formation of biofilms is still unclear. In this study, we present real-time, label-free monitoring of the interaction of Escherichia coli and Pseudomonas aeruginosa bacteria with untreated glass control surfaces and surfaces treated with benzalkonium chloride, a chemical compound known for its antimicrobial properties. The proof of principle investigation has been performed in a

SUBMITTER: Giorgi F 

PROVIDER: S-EPMC9616909 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature