Reliability and Validity of an Instrument of COVID-19 Patient-Reported Symptoms in Outpatients.

ABSTRACT:

Importance

Patient-reported outcome instruments are key in assessing COVID-19-related symptoms and associated burden. However, a valid and reliable instrument to assess symptom severity and progression among outpatients with COVID-19 is not yet available.

Objectives

To assess the extent to which the Symptoms Evolution of COVID-19 (SE-C19) instrument is valid, reliable, and able to detect symptom changes in outpatients with COVID-19, as well as to establish a definition of symptom resolution.

Design, setting, and participants

In this diagnostic/prognostic study, psychometric properties of SE-C19 were assessed in participants recruited into an ongoing, adaptive, phase 1/2/3, randomized, double-blind, placebo-controlled clinical trial, during 2020 to 2022. Adult outpatie

SUBMITTER: Rofail D 

PROVIDER: S-EPMC9617168 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature