Methodological quality of systematic reviews on treatments for Alzheimer's disease: a cross-sectional study.

ABSTRACT:

Background

Carefully conducted systematic reviews (SRs) can provide reliable evidence on the effectiveness of treatment strategies for Alzheimer's disease (AD). Nevertheless, the reliability of SR results can be limited by methodological flaws. This cross-sectional study aimed to examine the methodological quality of SRs on AD treatments, along with potentially relevant factors.

Methods

To identify eligible SRs on AD treatments, four databases including the Cochrane Database of Systematic Reviews, MEDLINE, EMBASE, and PsycINFO were searched. The Assessing the Methodological Quality of Systematic Reviews 2 instrument was used for quality appraisal of SRs. Multivariable regression analyses were used to examine factors related to methodological quality.

Results

A total o

SUBMITTER: Zhong CCW 

PROVIDER: S-EPMC9617345 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature