Mechanistic insights into the health benefits of fish-oil supplementation against fine particulate matter air pollution: a randomized controlled trial.

ABSTRACT:

Background

Dietary fish-oil supplementation might attenuate the associations between fine particulate matter (PM_2.5) and subclinical biomarkers. However, the molecular mechanisms remain to be elucidated. This study aimed to explore the molecular mechanisms of fish-oil supplementation against the PM_2.5-induced health effects.

Methods

We conducted a randomized, double-blinded, and placebo-controlled trial among healthy college students in Shanghai, China, from September 2017 to January 2018. A total of 70 participants from the Fenglin campus of Fudan University were included. We randomly assigned participants to either supplementation of 2.5-gram fish oil (n = 35) or sunflower-seed oil (placebo) (n = 35) per day and conducted four rounds of health measure

SUBMITTER: Zhou L 

PROVIDER: S-EPMC9617415 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature