Elevation of serum interleukin-1β levels as a potential indicator for malarial infection and severe malaria: a meta-analysis.

ABSTRACT:

Background

Interleukin (IL)-1β is a proinflammatory cytokine that has a role in disease-related inflammation, including malaria. However, reports on the effect of IL-1β on malaria severity are inconsistent. Therefore, meta-analyses to compare differences in IL-1β levels between patients with severe malaria, patients with uncomplicated malaria and healthy controls were performed.

Methods

The PRISMA standards were used to perform a systematic review and meta-analysis. A search of PubMed, Scopus, EMBASE and reference lists was conducted for articles providing data on IL-1β levels between patients with severe malaria, patients with uncomplicated malaria and healthy controls between January 1988 and March 2022, using a combination of search terms. The quality of all studies inclu

SUBMITTER: Mahittikorn A 

PROVIDER: S-EPMC9617441 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature