Depressive symptoms, cognitive impairment, and all-cause mortality among REGARDS participants with heart failure

ABSTRACT: Abstract

Aims

To ascertain whether depressive symptoms and cognitive impairment (CI) are associated with mortality among patients with heart failure (HF), adjusting for sociodemographic, comorbidities, and biomarkers.

Methods and results

We utilized Medicare-linked data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study, a biracial prospective ongoing cohort of 30 239 US community-dwelling adults, recruited in 2003–07. HF diagnosis was ascertained in claims analysis. Depressive symptoms were defined as a score ≥4 on the four-item Center for Epidemiological Studies-Depression scale. Cognitive impairment was defined as a score of ≤4 on the six-item screener that assessed three-item recall and orientation to year, month, and day of the week. Seq

SUBMITTER:  

PROVIDER: S-EPMC9617474 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature