Low dose peripheral systemic thrombolysis for treatment of intermediate-high risk acute pulmonary embolism: a case series.

ABSTRACT:

Background

The management of intermediate-high-risk acute pulmonary embolism (PE) is controversial with increasing interest in more aggressive treatment approaches than anticoagulation alone.

Case summary

We describe the case series of four consecutive patients who presented to emergency room for acute shortness of breath. They were diagnosed with intermediate-high-risk acute PE based on the computed tomography pulmonary angiography and transthoracic echocardiography (TTE) findings and the elevated simplified PE score index. They received bolus of 5 mg thrombolytics recombinant tissue plasminogen activator (rtPA) administered through peripheral intravenous (i.v.) line followed by continuous infusion at a rate of 2 mg/h along with unfractionated heparin (UFH) at a rate of 500

SUBMITTER: Charif F 

PROVIDER: S-EPMC9617477 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature