Exploring the Role of Antiviral Nasal Sprays in the Control of Emerging Respiratory Infections in the Community.

ABSTRACT:

Introduction

The COVID-19 pandemic has demonstrated that there is an unmet need for the development of novel prophylactic antiviral treatments to control the outbreak of emerging respiratory virus infections. Passive antibody-based immunisation approaches such as intranasal antibody prophylaxis have the potential to provide immediately accessible universal protection as they act directly at the most common route of viral entry, the upper respiratory tract. The need for such products is very apparent for SARS-CoV-2 at present, given the relatively low effectiveness of vaccines to prevent infection and block virus onward transmission. We explore the benefits and challenges of the use of antibody-based nasal sprays prior and post exposure to the virus.

Methods

The classic susce

SUBMITTER: Hadjichrysanthou C 

PROVIDER: S-EPMC9618272 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature