Disease Progression of Hospitalized Elderly Patients with Omicron BA.2 Treated with Molnupiravir.

ABSTRACT:

Introduction

The efficacy of molnupiravir (MLN) on Omicron sublineages is limited. We investigated the effectiveness of MLN in older adults diagnosed with Omicron BA.2.

Methods

Data of elderly COVID-19 patients (over 60 years) admitted to Chinghai Hospital (Shanghai, China) from 26 March to 31 May 2022 were reviewed. Study outcomes were a composite of undetectable viral load (VL) and disease progression [all-cause mortality, initiation of oxygen supply through high-flow device or invasive mechanical ventilation (IMV), or intensive care unit (ICU) admission] and their individual outcomes.

Results

A total of 42 elderly patients were enrolled: 26 of them received MLN, 17 (40.5%) were males, the median age was 84 years, and 12 were fully vaccinated (31.0%). Among these el

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9618302 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature