Structural and functional MRI evidence for significant contribution of precentral gyrus to flexible oculomotor control: evidence from the antisaccade task.

ABSTRACT: Antisaccade task requires inhibition of a prepotent prosaccade to a peripheral target and initiation of a saccade to the opposite location, and, therefore, is used as a tool to investigate behavioral adjustment. The frontal and parietal cortices are both known for their activation during saccade generation, but it is unclear whether their neuroanatomical characteristics also contribute to antisaccades. Here, we took antisaccade cost (antisaccade latency minus prosaccade latency) as an index for additional time for generating antisaccades. Fifty-eight participants conducted pro and antisaccade tasks outside the magnetic resonance imaging (MRI) scanner and their structural MRI (sMRI) data were also collected to explore brain regions neuroanatomically related to antisaccade cost. Then, twelve

SUBMITTER: Jin Z 

PROVIDER: S-EPMC9618498 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature