Cortical gradient of a human functional similarity network captured by the geometry of cytoarchitectonic organization.

ABSTRACT: Mapping the functional topology from a multifaceted perspective and relating it to underlying cross-scale structural principles is crucial for understanding the structural-functional relationships of the cerebral cortex. Previous works have described a sensory-association gradient axis in terms of coupling relationships between structure and function, but largely based on single specific feature, and the mesoscopic underpinnings are rarely determined. Here we show a gradient pattern encoded in a functional similarity network based on data from Human Connectome Project and further link it to cytoarchitectonic organizing principles. The spatial distribution of the primary gradient follows an inferior-anterior to superior-posterior axis. The primary gradient demonstrates converging relationsh

SUBMITTER: Meng Y 

PROVIDER: S-EPMC9618576 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature