Pubertal development underlies optimization of inhibitory control through specialization of ventrolateral prefrontal cortex.

ABSTRACT: Inhibitory control improves into young adulthood after specialization of relevant brain systems during adolescence. However, the biological mechanisms supporting this unique transition are not well understood. Given that adolescence is defined by puberty, we examined relative contributions of chronological age and pubertal maturation to inhibitory control development. 105 8-19-year-olds completed 1-5 longitudinal visits (227 visits total) in which pubertal development was assessed via self-reported Tanner stage and inhibitory control was assessed with an in-scanner antisaccade task. As expected, percentage and latency of correct antisaccade responses improved with age and pubertal stage. When controlling for pubertal stage, chronological age was distinctly associated with correct response

SUBMITTER: Ravindranath O 

PROVIDER: S-EPMC9618767 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature