Nosocomial malaria transmissions resolved by genomic analyses - a retrospective case report study in France (2007-2021).

ABSTRACT:

Background

Exposure of blood to malaria parasites can lead to infection even in the absence of the anopheles mosquito vector. During a stay in a healthcare facility, accidental inoculation of the skin with blood from a malaria patient might occur, referred to as nosocomial malaria transmission.

Methods

Between 2007 and 2021, we identified six autochthonous malaria cases that occurred in six different French hospitals, originating from nosocomial transmission and imported malaria patients being the infection source. Four cases were observed during the COVID-19 pandemic. The genetic relatedness between source and nosocomial infections was evaluated by genome-wide short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs).

Results

None of the patients with au

SUBMITTER: Coppee R 

PROVIDER: S-EPMC9619641 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature