Transforming and evaluating the UK Biobank to the OMOP Common Data Model for COVID-19 research and beyond.

ABSTRACT:

Objective

The COVID-19 pandemic has demonstrated the value of real-world data for public health research. International federated analyses are crucial for informing policy makers. Common data models (CDM) are critical for enabling these studies to be performed efficiently. Our objective was to convert the UK Biobank, a study of 500,000 participants with rich genetic and phenotypic data to the Observational Medical Outcomes Partnership (OMOP) CDM.

Materials and methods

We converted UK Biobank data to OMOP CDM v. 5.3. We transformedparticipant research data on diseases collected at recruitment and electronic health records (EHR) from primary care, hospitalizations, cancer registrations, and mortality from providers in England, Scotland, and Wales. We performed syntactic and se

SUBMITTER: Papez V 

PROVIDER: S-EPMC9619789 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature