Multimodal neuroimaging in post-COVID syndrome and correlation with cognition.

ABSTRACT: Brain changes have been reported in the first weeks after SARS-CoV-2 infection. However, limited literature exists about brain alterations in post-COVID syndrome, a condition increasingly associated with cognitive impairment. The present study aimed to evaluate brain functional and structural alterations in patients with post-COVID syndrome, and assess whether these brain alterations were related to cognitive dysfunction. Eighty-six patients with post-COVID syndrome and 36 healthy controls were recruited and underwent neuroimaging acquisition and a comprehensive neuropsychological assessment. Cognitive and neuroimaging examinations were performed 11 months after the first symptoms of SARS-CoV-2. Whole-brain functional connectivity analysis was performed. Voxel-based morphometry was perform

SUBMITTER: Diez-Cirarda M 

PROVIDER: S-EPMC9620345 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature