A method to obtain exact single-step GBLUP for non-genotyped descendants when the genomic relationship matrix of ancestors is not available.

ABSTRACT:

Background

Single-step genomic best linear unbiased prediction (GBLUP) involves a joint analysis of individuals with genotype information, and their ancestors, descendants, or contemporaries, without recorded genotypes. Livestock applications typically represent populations with fewer individuals with genotypes relative to the number not genotyped. Most breeding programmes are structured, consisting of a nucleus tier in which selection drives genetic gains that are propagated through descendants that represent parents in multiplier and commercial tiers. In some cases, the genotypes in the nucleus tier are proprietary to a breeding company, and not publicly available for a whole industry analysis. Bayesian inference involves combining a defined description of prior information with

SUBMITTER: Garrick DJ 

PROVIDER: S-EPMC9620661 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature