Ambient air pollution associated with incidence and dynamic progression of type 2 diabetes: a trajectory analysis of a population-based cohort.

ABSTRACT:

Background

Though the association between air pollution and incident type 2 diabetes (T2D) has been well documented, evidence on the association with development of subsequent diabetes complications and post-diabetes mortality is scarce. We investigate whether air pollution is associated with different progressions and outcomes of T2D.

Methods

Based on the UK Biobank, 398,993 participants free of diabetes and diabetes-related events at recruitment were included in this analysis. Exposures to particulate matter with a diameter ≤ 10 μm (PM₁₀), PM_2.5, nitrogen oxides (NO_x), and NO₂ for each transition stage were estimated at each participant's residential addresses using data from the UK's Department for Environment, Food and Rural Af

SUBMITTER: Wu Y 

PROVIDER: S-EPMC9620670 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature