A study of patient-reported pain during bone marrow aspiration and biopsy using local anesthesia alone compared with local anesthesia with intravenous midazolam coadministration at a tertiary academic hospital in South Africa.

ABSTRACT:

Introduction

During the bone marrow aspiration and biopsy (BMAB) procedure, patients report pain of widely variable intensity. There is limited literature on the factors associated with the pain. The use of local anesthesia (LA) only is still widespread although it does not abolish the pain. Midazolam is the most commonly used benzodiazepine for conscious sedation. Our center introduced universal midazolam sedation unless there is a contraindication to its use, 4 years ago. This study assessed the impact of the universal use of intravenous midazolam for BMAB compared to use of LA only. The factors associated with the pain of BMAB, were analyzed.

Methods

A retrospective cross-sectional study was performed on adult patients who had a BMAB procedure from July 1, 2018 to March 3

SUBMITTER: Alzanad F 

PROVIDER: S-EPMC9621466 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature