Sequence-Based Identification of Metronidazole-Resistant Clostridioides difficile Isolates.

ABSTRACT: The plasmid pCD-METRO confers metronidazole resistance in Clostridioides difficile. We showed high sequence similarity among pCD-METRO plasmids from different isolates and identified pCD-METRO and associated metronidazole-resistant isolates in clinical and veterinary reservoirs in the Americas. We recommend using PCR or genomic assays to detect pCD-METRO in metronidazole-resistant C. difficile.

SUBMITTER: Smits WK 

PROVIDER: S-EPMC9622256 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature