Portable comprehensive two-dimensional micro-gas chromatography using an integrated flow-restricted pneumatic modulator.

ABSTRACT: Two-dimensional (2D) gas chromatography (GC) provides enhanced vapor separation capabilities in contrast to conventional one-dimensional GC and is useful for the analysis of highly complex chemical samples. We developed a microfabricated flow-restricted pneumatic modulator (FRPM) for portable comprehensive 2D micro-GC (μGC), which enables rapid ²D injection and separation without compromising the ¹D separation speed and eluent peak profiles. ²D injection characteristics such as injection peak width and peak height were fully characterized by using flow-through micro-photoionization detectors (μPIDs) at the FRPM inlet and outlet. A ²D injection peak width of ~25 ms could be achieved with a ²D/¹D flow rate ratio over 10. The F

SUBMITTER: Huang X 

PROVIDER: S-EPMC9622416 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature