Evidence-based impact projections of single-dose human papillomavirus vaccination in India: a modelling study.

ABSTRACT:

Background

Despite the high burden of cervical cancer, access to preventive measures remains low in India. A single-dose immunisation schedule could facilitate the scale-up of human papillomavirus (HPV) vaccination, contributing to global elimination of cervical cancer. We projected the effect of single-dose quadrivalent HPV vaccination in India in comparison with no vaccination or to a two-dose schedule.

Methods

In this modelling study, we adapted an HPV transmission model (EpiMetHeos) to Indian data on sexual behaviour (from the Demographic and Health Survey and the Indian National AIDS Control Organisation), HPV prevalence data (from two local surveys, from the states of Tamil Nadu and West Bengal), and cervical cancer incidence data (from Cancer Incidence in Five Contine

SUBMITTER: Man I 

PROVIDER: S-EPMC9622421 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature