Long-term follow-up of patients undergoing renal sympathetic denervation.

ABSTRACT:

Objectives

Renal denervation (RDN) proved to significantly lower blood pressure (BP) at 2-6 months in patients on and off antihypertensive drugs. Given a lack of longer-term follow-up data, our aim was to assess the safety and efficacy of RDN up to five years taking into account antihypertensive drug regimen changes over time.

Methods

In the present single-center study, patients underwent RDN for (therapy resistant) hypertension. Patients underwent protocolized yearly follow-up out to five years. Data were collected on 24-h ambulatory BP and office BP monitoring, renal function, antihypertensive drug regimen, and safety events, including non-invasive renal artery imaging at 6/12 months. Efficacy analyses were performed using linear mixed-effects models.

Results

Sevent

SUBMITTER: Zeijen VJM 

PROVIDER: S-EPMC9622524 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature