Integrative analyses of genes about venous thromboembolism: An umbrella review of systematic reviews and meta-analyses.

ABSTRACT:

Background

In recent years, many studies have found possible links between gene polymorphisms and venous thromboembolism (VTE). By identifying genetic risk factors before facing environmental risk factors such as surgical interventions and COVID-19 vaccination, we could rapidly respond to the risk of VTE. The aim of this study was to perform an umbrella review of genetic variants related to VTE. Integrative gene analysis of VTE was performed to identify critical genetic variations.

Methods

This study conducted an umbrella review of systematic reviews and meta-analyses. All included studies were selected from the PubMed/MEDLINE database. To select eligible studies, the following variables were extracted: first author name; effect size of each study genetic variant; year of pu

SUBMITTER: Lee S 

PROVIDER: S-EPMC9622592 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature