The effect of probiotics on functional constipation in adults: A randomized, double-blind controlled trial.

ABSTRACT:

Background

Two formulations were developed in the form of an oral sachet containing probiotics, and their efficacy and safety were evaluated in adults with functional constipation.

Methods

One formulation with Lactobacillus acidophilus, Bifidobacterium bifidum and Lactobacillus rhamnosus (3 billion Colony Forming Units - CFU); and another with Lactobacillus acidophilus, Bifidobacterium bifidum, Lactobacillus rhamnosus, Lactobacillus paracasei, Bifidobacterium longum, Bifidobacterium lactis, Lactobacillus casei, Bifidobacterium animallis (8 billion CFU). The participants were randomized in a 3-arm parallel study and one oral sachet was auto-administered once a day for 30 days.

Results

Primary outcomes were improvement in increasing the frequency of weekly bowel movemen

SUBMITTER: Mitelmao FCR 

PROVIDER: S-EPMC9622669 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature