Multiplex array analysis of serum cytokines offers minimal predictive value for cognitive function in the subacute phase after stroke.

ABSTRACT:

Objective

The effects of inflammation on post-stroke cognitive function are still unclear. This study investigated the correlation between the Th17-related cytokines in peripheral blood and post-stroke cognitive function after ischemic stroke in the subacute phase.

Design

A retrospective cohort study.

Setting

Academic acute inpatient rehabilitation facility.

Participants

One hundred and fourteen patients with first ischemic stroke were categorized as the poor cognitive recovery group (n = 58) or good cognitive recovery group (n = 56) based on their cognitive MRFS efficiency.

Interventions

All subjects received routine physical, occupational, and speech-language pathology therapy.

Main outcome measures

Serum cytokines/chemokine (IL-1

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9622930 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature