Brain white matter hyperintensities in Kawasaki disease: A case-control study.

ABSTRACT:

Background

Cerebrovascular involvement of Kawasaki disease (KD) is poorly studied. White matter hyperintensities (WMH) indicate cerebral small vessel disease and increase the risk for stroke.

Purpose

To investigate whether childhood KD is associated with WMHs and other cerebrovascular findings later in adulthood.

Materials and methods

In this case-control study, patients diagnosed with KD (cases) at our tertiary hospital between 1978 and 1995 were invited to brain magnetic resonance (MRI) between 2016 and 2017. Migraine patients (controls) with available brain MRI were matched with cases (ratio 4:1) by age (±2 years) and sex. Two blinded neuroradiologists evaluated independently cerebrovascular findings from the brain MRI scans. Modified Scheltens' visual rating scale

SUBMITTER: Laukka D 

PROVIDER: S-EPMC9623056 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature