Hyperthermic intraperitoneal chemotherapy following up-front cytoreductive surgery versus cytoreductive surgery alone for isolated synchronous colorectal peritoneal metastases: A retrospective, observational study.

ABSTRACT:

Background

To date, the value of hyperthermic intraperitoneal chemotherapy (HIPEC) following up-front resection for isolated synchronous colorectal peritoneal metastases seems controversial.

Patients and methods

This retrospective cohort study was conducted from September 1, 2012, to September 1, 2019, at a tertiary medical center in China. Patients with isolated synchronous colorectal peritoneal metastases were included in CRS plus HIPEC group or CRS alone group based on the treatment history. Overall survival and relapse-free survival were estimated using Cox proportional hazards regression analysis and Kaplan-Meier method.

Results

78 patients with isolated synchronous colorectal peritoneal metastases were identified among 396 patients with synchronous colorectal pe

SUBMITTER: Qin X 

PROVIDER: S-EPMC9623104 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature