Intraindividual Reliability of Opportunistic Computed Tomography-Assessed Adiposity and Skeletal Muscle among Breast Cancer Patients.

ABSTRACT:

Background

Adiposity and skeletal muscle levels assessed on computed tomography (CT) scans are prognostic indicators for patients with breast cancer. However, the intraindividual reliability of temporal changes in body composition assessed on opportunistic CT scans is unclear.

Methods

This retrospective study included 50 patients newly diagnosed with breast cancer who had archived CT scans pre- and post-surgery for breast cancer. The third lumbar CT image was segmented for areas of three types of adipose tissues and five different densities of skeletal muscles. Mean and percent changes in areas pre- vs. post-surgery were compared using Wilcoxon signed rank tests. Intraclass correlation coefficients (ICCs) with 95% CIs were assessed. A two-sided p < 0.05 was considered statis

SUBMITTER: Aduse-Poku L 

PROVIDER: S-EPMC9623424 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature