Structural disconnections associated with language impairments in chronic post-stroke aphasia using disconnectome maps.

ABSTRACT: Inconsistent findings have been reported about the impact of structural disconnections on language function in post-stroke aphasia. This study investigated patterns of structural disconnections associated with chronic language impairments using disconnectome maps. Seventy-six individuals with post-stroke aphasia underwent a battery of language assessments and a structural MRI scan. Support-vector regression disconnectome-symptom mapping analyses were performed to examine the correlations between disconnectome maps, representing the probability of disconnection at each white matter voxel and different language scores. To further understand whether significant disconnections were primarily representing focal damage or a more extended network of seemingly preserved but disconnected areas beyo

SUBMITTER: Billot A 

PROVIDER: S-EPMC9623824 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature