Association of alcohol use with memory decline in middle-aged and older Chinese: a longitudinal cohort study.

ABSTRACT:

Background

Previous studies on associations of alcohol use with memory decline showed inconclusive results. We examined these associations using longitudinal data from the Guangzhou Biobank Cohort Study (GBCS) and explored whether these associations varied by sex and age group.

Methods

Memory function was assessed by delayed 10-word recall test (DWRT) and immediate 10-word recall test (IWRT) at both baseline (2003-2008) and follow-up (2008-2012) examinations, expressed as the mean annual change and mean annual rate of change in scores. Memory cognitive impairment was defined by DWRT scores of less than 4. Multivariable linear regression models and restricted cubic spline were used for data analysis.

Results

Of 14,827 participants without memory cognitive impairment at

SUBMITTER: Tian YM 

PROVIDER: S-EPMC9623936 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature