Genome-wide detection of RNA editing events during the hair follicles cycle of Tianzhu white yak.

ABSTRACT:

Background

The hair coat is available for the yak to live in the harsh environment of the plateau. Besides, improving the hair production of yak is necessary for its textile industry development. Hair grows from hair follicles (HFs). The HFs undergo periodic growth after birth and are regulated by the complex gene regulatory network. However, the molecular mechanism of HFs regeneration in the Tianzhu white yak remains unclear. RNA editing is a post-transcriptional mechanism that regulates gene expression and produces new transcripts. Hence, we investigated the influence of the A-to-I RNA editing events on the HFs cycle of the Tianzhu white yak.

Results

We finally identified 54,707 adenosine-to-inosine (A-to-I) RNA editing sites (RESs) from RNA sequencing data of the HFs cycl

SUBMITTER: Zhou X 

PROVIDER: S-EPMC9624038 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature