Bioconjugation Strategies for Tobacco Mild Green Mosaic Virus.

ABSTRACT: Tobacco mild green mosaic virus (TMGMV) is a plant virus closely related to Tobacco mosaic virus (TMV), sharing many of its structural and chemical features. These rod-shaped viruses, comprised of 2130 identical coat protein subunits, have been utilized as nanotechnological platforms for a myriad of applications, ranging from drug delivery to precision agriculture. This versatility for functionalization is due to their chemically active external and internal surfaces. While both viruses are similar, they do exhibit some key differences in their surface chemistry, suggesting the reactive residue distribution on TMGMV should not overlap with TMV. In this work, we focused on the establishment and refinement of chemical bioconjugation strategies to load molecules into or onto TMGMV for targete

SUBMITTER: Gonzalez-Gamboa I 

PROVIDER: S-EPMC9624232 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature