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Longitudinal antibody response kinetics following SARS-CoV-2 messenger RNA vaccination in pregnant and nonpregnant persons.


ABSTRACT:

SUBMITTER: Prabhu M 

PROVIDER: S-EPMC9626404 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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<h4>Background</h4>For some vaccine-preventable diseases, the immunologic response to vaccination is altered by a pregnant state. The effect of pregnancy on SARS-CoV-2 vaccine response remains unclear.<h4>Objective</h4>We sought to characterize the peak and longitudinal anti-S immunoglobulin G, immunoglobulin M, and immunoglobulin A responses to messenger RNA-based SARS-CoV-2 vaccination in pregnant persons and compare them with those in nonpregnant, reproductive-aged persons.<h4>Study design</h  ...[more]

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