Conservative oxygen therapy in critically ill and perioperative period of patients with sepsis-associated encephalopathy.

ABSTRACT:

Objectives

Sepsis-associated encephalopathy (SAE) patients in the intensive care unit (ICU) and perioperative period are administrated supplemental oxygen. However, the correlation between oxygenation status with SAE and the target for oxygen therapy remains unclear. This study aimed to examine the relationship between oxygen therapy and SAE patients.

Methods

Patients diagnosed with sepsis 3.0 in the intensive care unit (ICU) were enrolled. The data were collected from the Medical Information Mart for Intensive Care IV (MIMIC IV) database and the eICU Collaborative Research Database (eICU-CRD) database. The generalized additive models were adopted to estimate the oxygen therapy targets in SAE patients. The results were confirmed by multivariate Logistic, propensity score ana

SUBMITTER: Li Y 

PROVIDER: S-EPMC9626799 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature