Sustained detection of type 2 poliovirus in London sewage between February and July, 2022, by enhanced environmental surveillance.

ABSTRACT:

Background

The international spread of poliovirus exposes all countries to the risk of outbreaks and is designated a Public Health Emergency of International Concern by WHO. This risk can be exacerbated in countries using inactivated polio vaccine, which offers excellent protection against paralysis but is less effective than oral vaccine against poliovirus shedding, potentially allowing circulation without detection of paralytic cases for long periods of time. Our study investigated the molecular properties of type 2 poliovirus isolates found in sewage with an aim to detect virus transmission in the community.

Methods

We performed environmental surveillance in London, UK, testing sewage samples using WHO recommended methods that include concentration, virus isolation in cel

SUBMITTER: Klapsa D 

PROVIDER: S-EPMC9627700 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature