Prevalence and Prognostic Significance of Frailty in Asian Patients With Heart Failure: Insights From ASIAN-HF.

ABSTRACT:

Background

Frailty is common in patients with heart failure (HF) and can adversely impact outcomes.

Objectives

This study examined the prevalence of frailty among Asian patients with HF, its association with 1-year outcomes, and if race-ethnicity, HF subtypes, and sex modify this relationship.

Methods

In the multinational ASIAN-HF (Asian Sudden Cardiac Death in Heart Failure) registry, a baseline frailty index (FI) was constructed using a cumulative deficits approach with 48 baseline variables, and patients were followed for the 1-year primary outcome of all-cause death or HF hospitalization.

Results

Among 3,881 participants (age 61 ± 13 years, 27% female), the mean FI was 0.28 ± 0.11, and 69% were frail (FI >0.21). Higher FI was associated with older age, Mala

SUBMITTER: Aung T 

PROVIDER: S-EPMC9627805 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature