Differences in Plaque Characteristics and Myocardial Mass: Implications for Physiological Significance.

ABSTRACT:

Background

The mechanism of the fractional flow reserve (FFR) difference according to sex has not been clearly understood.

Objectives

This study sought to evaluate sex differences in coronary stenosis, plaque characteristics, and left ventricular (LV) mass and their implications for physiological significance.

Methods

This was a post hoc analysis of a pooled population of multicenter, international prospective cohorts. Patients (166 women and 489 men) underwent coronary computed tomography angiography (CCTA) within 90 days before invasive FFR measurements were included. The minimal lumen area, percent of plaque burden, whole vessel plaque volume by composition, high-risk plaque characteristics, and LV mass were analyzed from CCTA images.

Results

Among 1,188 ves

SUBMITTER: Kim CH 

PROVIDER: S-EPMC9627886 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature