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Dataset Information

Influence of Baseline HbA1c and Antiplatelet Therapy on 1-Year Vein Graft Outcome.


ABSTRACT:

Background

The influence of baseline HbA1c levels on vein graft outcomes post coronary artery bypass grafting (CABG) remains unclear.

Objective

The purpose of this study was to assess the association between baseline HbA1c and 1-year vein graft patency, and the effects of antiplatelet therapy on the 1-year vein graft patency after CABG in patients with baseline HbA1c <6.5% vs ≥6.5%.

Methods

We examined the subgroups with baseline HbA1c <6.5% vs ≥6.5% from the DACAB trial (NCT02201771), in which 500 patients were randomly allocated to receive ticagrelor plus aspirin (T+A), ticagrelor alone (T), or aspirin alone (A) for 1 year after CABG. The primary outcome was the vein graft patency (FitzGibbon grade A) at 1 year.

Results

A total of 405 patients with available

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC9627937 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature

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