Soluble Corin Predicts the Risk of Cardiovascular Disease: A 10-Year Follow-Up Study.

ABSTRACT:

Background

As a key enzyme of the natriuretic peptides system, corin may participate in the development of cardiovascular disease (CVD). Its level in circulation predicted CVD recurrence in patients with myocardial infarction and heart failure, but no study examined this prediction in general populations.

Objectives

This study sought to examine the prospective association between corin and CVD in a community-based population of Chinese adults.

Methods

The Gusu cohort included 2,498 participants (mean age 53 years, 39% men) who were free of CVD at baseline. Serum corin was measured by enzyme-linked immunosorbent assay kits at baseline and CVD events were followed every 2 years for all participants. A competing-risks survival regression model was used to examine the ass

SUBMITTER: Chen L 

PROVIDER: S-EPMC9627939 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature