Outbreak of human monkeypox in Nigeria in 2017-18: a clinical and epidemiological report.

ABSTRACT:

Background

In September, 2017, human monkeypox re-emerged in Nigeria, 39 years after the last reported case. We aimed to describe the clinical and epidemiological features of the 2017-18 human monkeypox outbreak in Nigeria.

Methods

We reviewed the epidemiological and clinical characteristics of cases of human monkeypox that occurred between Sept 22, 2017, and Sept 16, 2018. Data were collected with a standardised case investigation form, with a case definition of human monkeypox that was based on previously established guidelines. Diagnosis was confirmed by viral identification with real-time PCR and by detection of positive anti-orthopoxvirus IgM antibodies. Whole-genome sequencing was done for seven cases. Haplotype analysis results, genetic distance data, and epidemiologi

SUBMITTER: Yinka-Ogunleye A 

PROVIDER: S-EPMC9628943 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature