Gastroparesis in systemic sclerosis: a detailed analysis using whole-gut scintigraphy.

ABSTRACT:

Objectives

Gastroparesis is a common complication of SSc. We sought to determine the degree of overlap between gastroparesis and dysmotility in other areas of the gut, correlate our findings with gastrointestinal (GI) symptoms, and examine associations between gastroparesis and SSc features.

Methods

Whole-gut scintigraphy was performed on SSc patients who were enrolled in the Johns Hopkins Scleroderma Cohort, for whom detailed longitudinal clinical and serologic data are collected. A subset of patients completed the University of California Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract Instrument 2.0 (UCLA GIT 2.0) to quantify their GI symptoms. We examined associations between the presence and severity of gastroparesis, GI symptoms, and SSc clinic

SUBMITTER: Adler B 

PROVIDER: S-EPMC9629369 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature