Prevalence of frailty in patients with polymyalgia rheumatica and association with health-related quality of life, cognition and sarcopenia.

ABSTRACT:

Objective

To describe the prevalence of frailty in a single-centre cohort of patients with PMR and describe its association with health-related quality of life (HRQoL), cognition and sarcopenia.

Methods

This was a cross-sectional study of patients with PMR, according to 2012 EULAR/ACR Classification Criteria, presenting within 12 months of diagnosis and on treatment with glucocorticoids. Frailty was defined according to the Fried frailty criteria. HRQoL was assessed using Patient-Reported Outcomes Measurement Information System Computerized Adaptive Test (PROMIS-CAT) and cognition was assessed using the Mini-Mental State Examination. Sarcopenia was measured by DXA.

Results

Forty-one patients were enrolled. Prevalence of frailty and pre-frailty was 17% and 59%, respect

SUBMITTER: Sattui SE 

PROVIDER: S-EPMC9629413 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature