Differences in temporal processing speeds between the right and left auditory cortex reflect the strength of recurrent synaptic connectivity.

ABSTRACT: Brain asymmetry in the sensitivity to spectrotemporal modulation is an established functional feature that underlies the perception of speech and music. The left auditory cortex (ACx) is believed to specialize in processing fast temporal components of speech sounds, and the right ACx slower components. However, the circuit features and neural computations behind these lateralized spectrotemporal processes are poorly understood. To answer these mechanistic questions we use mice, an animal model that captures some relevant features of human communication systems. In this study, we screened for circuit features that could subserve temporal integration differences between the left and right ACx. We mapped excitatory input to principal neurons in all cortical layers and found significantly stro

SUBMITTER: Neophytou D 

PROVIDER: S-EPMC9629599 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature